BM2021 BIOFLUIDS AND DYNAMICS SYLLABUS | ANNA UNIVERSITY BE BIOMEDICAL ENGG 6TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY SIXTH SEMESTER B.E BIOMEDICAL ENGINEERING DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS,EXAM PORTIONS,QUESTION BANK,PREVIOUS YEAR QUESTION PAPERS,MODEL QUESTION PAPERS, CLASS NOTES, IMPORTANT 2 MARKS, 8 MARKS, 16 MARKS TOPICS. IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI, TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
BM2021 BIOFLUIDS AND DYNAMICS L T P C
3 0 0 3
UNIT I 10
BIO-FLUID MECHANICS: Newton’s laws, Stress, Strain, Elasticity, Hooks-law, viscosity,
Newtonian fluid, Non-Newtonian fluid, Viscoelastic fluids, vascular tree, Relationship
between diameter, velocity and pressure of blood flow, Resistance against flow.
BIOVISCOELASTIC FLUID: Viscoelasticity - Viscoelastic models, Maxwell, Voigt and
Kelvin Models, Response to Harmonic variation, Use of viscoelastic models, Bio-
Viscoelastic fluids: Protoplasm, Mucus, Saliva, Synovial fluids.
UNIT II 10
FLOW PROPERTIES OF BLOOD: Physical, Chemical and Rheological properties of
blood. Apparent and relative viscosity, Blood viscosity variation: Effect of shear rate,
hematocrit, temperature, protein contents of blood. Casson’s equation, Problems
associated with extracorporeal blood flow. RHEOLOGY OF BLOOD IN MICROVESSELS:
Fahraeus -Lindquist effect and inverse effect, distribution of suspended particles in a
narrow rigid tube. Nature of red blood cells in tightly fitting tubes, hematocrit in very narrow
tube.
65
UNIT III 9
CARDIAC MECHANICS: Cardiovascular system. Mechanical properties of blood vessels:
arteries, arterioles, capillaries and veins. Blood flow: Laminar and
Turbulent, Physics of cardiovascular diseases, Prosthetic heart valves and replacements.
RESPIRATORY MECHANICS: Alveoli mechanics, Interaction of Blood and Lung P-V
curve of Lung: Breathing mechanism, Airway resistance, Physics of Lung diseases.
UNIT IV 8
SOFT TISSUE MECHANICS: Pseudo elasticity, non-linear stress-strain relationship,
Viscoelasticity, Structure, function and mechanical properties of skin, ligaments and
tendons.
UNIT V 8
ORTHOPEDIC MECHANICS: Mechanical properties of cartilage, diffusion properties of
Articular cartilage, mechanical properties of bone, kinetics and kinematics of joints,
lubrication of joints.
TEXT BOOKS:
1. Y.C Fung, Biomechanics- Mechanical properties of living tissues,2nd ed, Springer-
Verlag, 1993.
2. D.O Cooney, Biomedical engineering Principles. Marcel Dekker, INC New York.1976.
REFERENCE:
1. Silver Frederick H. Biomaterials, Medical Devices & Tissue Engineering: Chapman &
Hall, London, 1994
2. Biomechanics by Nihanth ozkai, D.A Mc Donald, Blood flow in arteries, Edward Arnold
ltd, 1998
BM2021 BIOFLUIDS AND DYNAMICS L T P C
3 0 0 3
UNIT I 10
BIO-FLUID MECHANICS: Newton’s laws, Stress, Strain, Elasticity, Hooks-law, viscosity,
Newtonian fluid, Non-Newtonian fluid, Viscoelastic fluids, vascular tree, Relationship
between diameter, velocity and pressure of blood flow, Resistance against flow.
BIOVISCOELASTIC FLUID: Viscoelasticity - Viscoelastic models, Maxwell, Voigt and
Kelvin Models, Response to Harmonic variation, Use of viscoelastic models, Bio-
Viscoelastic fluids: Protoplasm, Mucus, Saliva, Synovial fluids.
UNIT II 10
FLOW PROPERTIES OF BLOOD: Physical, Chemical and Rheological properties of
blood. Apparent and relative viscosity, Blood viscosity variation: Effect of shear rate,
hematocrit, temperature, protein contents of blood. Casson’s equation, Problems
associated with extracorporeal blood flow. RHEOLOGY OF BLOOD IN MICROVESSELS:
Fahraeus -Lindquist effect and inverse effect, distribution of suspended particles in a
narrow rigid tube. Nature of red blood cells in tightly fitting tubes, hematocrit in very narrow
tube.
65
UNIT III 9
CARDIAC MECHANICS: Cardiovascular system. Mechanical properties of blood vessels:
arteries, arterioles, capillaries and veins. Blood flow: Laminar and
Turbulent, Physics of cardiovascular diseases, Prosthetic heart valves and replacements.
RESPIRATORY MECHANICS: Alveoli mechanics, Interaction of Blood and Lung P-V
curve of Lung: Breathing mechanism, Airway resistance, Physics of Lung diseases.
UNIT IV 8
SOFT TISSUE MECHANICS: Pseudo elasticity, non-linear stress-strain relationship,
Viscoelasticity, Structure, function and mechanical properties of skin, ligaments and
tendons.
UNIT V 8
ORTHOPEDIC MECHANICS: Mechanical properties of cartilage, diffusion properties of
Articular cartilage, mechanical properties of bone, kinetics and kinematics of joints,
lubrication of joints.
TEXT BOOKS:
1. Y.C Fung, Biomechanics- Mechanical properties of living tissues,2nd ed, Springer-
Verlag, 1993.
2. D.O Cooney, Biomedical engineering Principles. Marcel Dekker, INC New York.1976.
REFERENCE:
1. Silver Frederick H. Biomaterials, Medical Devices & Tissue Engineering: Chapman &
Hall, London, 1994
2. Biomechanics by Nihanth ozkai, D.A Mc Donald, Blood flow in arteries, Edward Arnold
ltd, 1998
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