BT2305 MOLECULAR BIOLOGY SYLLABUS | ANNA UNIVERSITY B.TECH. BIOTECHNOLOGY 5TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY FIFTH SEMESTER B.TECH. BIOTECHNOLOGY DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS, IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009
BT2305 MOLECULAR BIOLOGY L T P C
3 0 0 3
UNIT I CLASSICAL GENETICS 5
Mendelian genetics, linkage, crossing over, classical experiments – Hershey and Chase,
Avery McLeod & McCarty.Bacterial conjugation, transduction and transformation.
UNIT II STRUCTURE OF NUCLEIC ACIDS AND DNA REPLICATION 15
Conformation of DNA and RNA; replication in prokaryotes, D-loop and rolling circle
mode of replication, replication of linear viral DNA. Organisation of eukaryotic
chromosome – cot value, replication of telomeres in eukaryotes
UNIT II I TRANSCRIPTION 8
In prokaryotes and eukaryotes, features of promoters and enhancers, transcription
factors, nuclear RNA splicing, ribozyme.
UNIT IV TRANSLATION 3 10
Elucidation of genetic code, mechanism, codon usage, suppressor mutation.
UNIT V REGULATION OF GENE EXPRESSION 7
Lac and trp phage life cycle, mutation and repair of DNA.operon ,
TOTAL : 45 PERIODS
TEXT BOOKS
1. Friefelder David, “Molecular Biology”, 2nd edition Narosa Publ. House. 1999
2. Lewin Benjamin,” Gene VIII”, Pearson Education,2004.
3. Watson JD., “Molecular Biology of the Gene”, 5th edition,Pearson Education, 2004.
42
REFERENCE
1. Weaver , R.F ,” Molecular Biology”, 3rd edition , Mc Grraw Hill, 2005.
BT2305 MOLECULAR BIOLOGY L T P C
3 0 0 3
UNIT I CLASSICAL GENETICS 5
Mendelian genetics, linkage, crossing over, classical experiments – Hershey and Chase,
Avery McLeod & McCarty.Bacterial conjugation, transduction and transformation.
UNIT II STRUCTURE OF NUCLEIC ACIDS AND DNA REPLICATION 15
Conformation of DNA and RNA; replication in prokaryotes, D-loop and rolling circle
mode of replication, replication of linear viral DNA. Organisation of eukaryotic
chromosome – cot value, replication of telomeres in eukaryotes
UNIT II I TRANSCRIPTION 8
In prokaryotes and eukaryotes, features of promoters and enhancers, transcription
factors, nuclear RNA splicing, ribozyme.
UNIT IV TRANSLATION 3 10
Elucidation of genetic code, mechanism, codon usage, suppressor mutation.
UNIT V REGULATION OF GENE EXPRESSION 7
Lac and trp phage life cycle, mutation and repair of DNA.operon ,
TOTAL : 45 PERIODS
TEXT BOOKS
1. Friefelder David, “Molecular Biology”, 2nd edition Narosa Publ. House. 1999
2. Lewin Benjamin,” Gene VIII”, Pearson Education,2004.
3. Watson JD., “Molecular Biology of the Gene”, 5th edition,Pearson Education, 2004.
42
REFERENCE
1. Weaver , R.F ,” Molecular Biology”, 3rd edition , Mc Grraw Hill, 2005.
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