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FT 3302 BIOCHEMICAL ENGINEERING II SYLLABUS | ANNA UNIVERSITY B.TECH. FOOD TECHNOLOGY 5TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013

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FT 3302 BIOCHEMICAL ENGINEERING II SYLLABUS | ANNA UNIVERSITY B.TECH. FOOD TECHNOLOGY 5TH SEMESTER SYLLABUS REGULATION 2008 2011 2012-2013 BELOW IS THE ANNA UNIVERSITY FIFTH SEMESTER B.TECH. FOOD TECHNOLOGY DEPARTMENT SYLLABUS, TEXTBOOKS, REFERENCE BOOKS, IT IS APPLICABLE FOR ALL STUDENTS ADMITTED IN THE YEAR 2011 2012-2013 (ANNA UNIVERSITY CHENNAI,TRICHY,MADURAI,TIRUNELVELI,COIMBATORE), 2008 REGULATION OF ANNA UNIVERSITY CHENNAI AND STUDENTS ADMITTED IN ANNA UNIVERSITY CHENNAI DURING 2009

FT 3302 BIOCHEMICAL ENGINEERING II L T P C
3 0 0 3
UNIT I STERILIZATION KINETICS 5
Thermal death kinetics of microorganisms, batch and continuous heat sterilization of liquid
media, filter sterilization of liquid media, air sterilization and design of sterilization equipment
- batch and continuous.
UNIT II METABOLIC STOICHIOMETRY AND ENERGETICS 12
Stoichiometry of cell growth and product formation, elemental balances, degrees of
reduction of substrate and biomass, available electron balances, yield coefficients of
biomass and product formation, maintenance coefficients energetic analysis of microbial
growth and product formation, oxygen consumption and heat evolution in aerobic cultures,
thermodynamic efficiency of growth.
UNIY III KINETICS OF MICROBIAL GROWTH AND PRODUCT FORMATION -
UNSTRUCTURED KINETIC MODELS 8
Modes of operation - batch, fed batch and continuous cultivation. Simple unstructured kinetic
models for microbial growth, Monod model, growth of filamentous organisms, product
formation kinetics - leudeking-piret models, substrate and product inhibition on cell growth
and product formation.
UNIT IV KINETICS OF MICROBIAL GROWTH AND PRODUCT FORMATIONSTRUCTURED
KINETIC MODELS 8
Study of structured models for analysis of various bioprocess – compartmental models,
models of cellular energetics and metabolism, single cell models, plasmid replication and
plasmid stability model.
UNIT V BIOREACTOR SCALE – UP 12
Regime analysis of bioreactor processes, oxygen mass transfer in bioreactors – Mass
transfer Coefficient- methods for the determination of mass transfer coefficients; mass
transfer correlations. Power requirements of Bioreactors. Scale-up considerations on heat
transfer oxygen transfer, power consumption and impeller tip speed.
TOTAL : 45 PERIODS
TEXT BOOKS
1. Lee, James M. “Biochemical Engineering”, PHI,1992.
2. Shuler, M.L. and Kargi, F. “Bioprocess Engineering : Basic Concepts”, 2ndEdition, PHI,
2002.
3. Bailey, J.E. and Ollis, D.F. “Biochemical Engineering Fundamentals” 2nd Edition,
McGraw – Hill, 1988.
4. Blanch, H.W. and Clark, D.S. “Biochemical Engineering”, Marcel Decker Inc., 1997.
39
REFERENCES
1. Moser, Anton. “Bioprocess Technology : Kinetics and Reactors”, Springer – Verlag,
1988.
2. Stanbury, P.F. etal. “Principles of Fermentation Technology”, 2nd Edition,Butterworth –
Heinemann / Elsevier, 1995.

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